Nami is a browser based wallet extension to interact with the Cardano blockchain and is non-custodial. It can be used to send and store multiple assets, to delegate, to mint tokens, use multi-sigs and much more

Daedalus is a full node wallet. This means that unlike light wallets (e.g.Yoroi, Adalite etc.) Daedalus downloads a full copy of the Cardano blockchain and independently validates every transaction in its history. That way you get maximum security and completely trustless operation, without centrally hosted 3rd party servers.